Monoclonal antibody to CD16 (Clone: B73.1) No Azide, Low Endotoxin
Produktgrößen
100ug
£429,00
10-4206-NALE-100UG
Über dieses Produkt
- SKU:
- 10-4206-NALE
- Zusätzliche Namen:
- CD16-II; CD16a antigen; Fc-gamma RIII-alpha; FcR-10; IgG Fc receptor III-2; CD16A; FCG3; FCGR3; IGFR3
- Anwendung:
- Immunofluorescence
- translate.label.attr.clone:
- B73.1
- Klonalität:
- Monoclonal
- Weitere Details:
- CD16, also known as low affinity IgG receptor III (FcgammaRIII), is expressed as two distinct forms, referred to as CD16a and CD16b. CD16a (FcgammaRIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein expressed on the surface of NK cells, activated monocytes, macrophages, a subset of T cells, and placental trophoblasts in humans. CD16b (FcgammaRIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein whose extracellular domain is over 95% homologous to that of CD16a, and is expressed specifically on neutrophils. CD16 binds to aggregated IgG or IgG-antigen complex, which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC).
- Format:
- Purified
- Gendetails:
- FCGR3A
- Host:
- Mouse
- Immunogen:
- NK cell-enriched fraction from human peripheral blood was used as the immunogen for this antibody.
- Isotyp:
- Mouse IgG1k
- Aufreinigung:
- Protein G Chromatography
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:10-4206-NALE.png