Monoclonal Antibody to CD20 (Clone: ABM46C7)
Produktgrößen
25ug
£319,00
10-4162-25UG
100ug
£375,00
10-4162-100UG
Über dieses Produkt
- SKU:
- 10-4162
- Zusätzliche Namen:
- MS4A1||CD20
- translate.label.attr.clone:
- ABM46C7
- Klonalität:
- Monoclonal
- Weitere Details:
- CD20 is clinically validated as an immunotherapy target for B-cell lymphomas and autoimmune diseases. CD20 consists of large, intracellular, amino- and carboxyterminal portions connected by 4 membrane-spanning domains. Its high expression on malignant B cells and its reported lack of shedding from the surfacemake CD20 an ideal target for antibody-mediated killing. Anti-CD20 antibodies are believed to mediate the therapeutic effect by activation of complement-dependent cytotoxicity (CDC) and largely by antibody-dependent cellular cytotoxicity exerted by recruitment of innate immune effector cells expressing the Fcgamma receptor IIIa.
- Format:
- Purified
- Gendetails:
- MS4A1
- Host:
- Mouse
- Immunogen:
- A partial length recombinant protein corresponding to extra cellular domain of CD20 was used as the immunogen for this antibody.
- Isotyp:
- Mouse IgG2b Kappa
- Aufreinigung:
- Protein G Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:FLOW1.jpg
