Monoclonal Antibody to CD20 (Clone: B9E9) FITC Conjugated
Produktgrößen
25ug
£319,00
10-4155-F-25UG
100ug
£429,00
10-4155-F-100UG
Über dieses Produkt
- SKU:
- 10-4155-F
- Zusätzliche Namen:
- B-lymphocyte antigen CD20||B-lymphocyte surface antigen B1||Bp35||Leukocyte surface antigen Leu-16||Membrane-spanning 4-domains subfamily A member 1||CD_antigen: CD20
- translate.label.attr.clone:
- B9E9
- Klonalität:
- Monoclonal
- Konjugat:
- FITC
- Weitere Details:
- CD20 is clinically validated as an immunotherapy target for B-cell lymphomas and autoimmune diseases. CD20 consists of large, intracellular, amino- and carboxyterminal portions connected by 4 membrane-spanning domains. Its high expression on malignant B cells and its reported lack of shedding from the surface make CD20 an ideal target for antibody-mediated killing. Anti-CD20 antibodies are believed to mediate the therapeutic effect by activation of complement-dependent cytotoxicity (CDC) and largely by antibody-dependent cellular cytotoxicity exerted by recruitment of innate immune effector cells expressing the Fcgamma receptor IIIa.
- Format:
- Purified
- Gendetails:
- MS4A1
- Host:
- Mouse
- Immunogen:
- Lymphoblastoid cell line Daudi was used as the immunogen for this antibody.
- Isotyp:
- Mouse IgG2a, Kappa
- Aufreinigung:
- Protein G Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg