Monoclonal Antibody to Human CD33 (Clone: wm53)
Produktgrößen
25ug
£319,00
10-4138-25UG
100ug
£375,00
10-4138-100UG
Über dieses Produkt
- SKU:
- 10-4138
- Zusätzliche Namen:
- Myeloid cell surface antigen CD33||Sialic acid-binding Ig-like lectin 3||Siglec-3||gp67
- translate.label.attr.clone:
- wm53
- Klonalität:
- Monoclonal
- Weitere Details:
- CD33 is a member of the SIGLEC (Sialic Acid-Binding Ig-Like Lectin) family of receptors, and the gene comprises seven coding exons. Exon 2 encodes the canonical IgV domain, exon 4 encodes the IgC structural domain, and exons 6 and 7 encode cytosolic ITIMs (Immunotyrosine Inhibitory Motifs). CD33 acts as a cell surface antigen which is expressed on normal myeloid cells and CD34+ blasts in AML (Acute Myeloid Leukemia). The antigen serves as a target of GO (Gemtuzumab/Ozogamicin), which exerts anti-leukemic effects in refractory AML.
- Format:
- Purified
- Gendetails:
- CD33
- Host:
- Mouse
- Immunogen:
- Human AML cells were used as immunogen for this antibody.
- Isotyp:
- Mouse IgG1 Kappa
- Aufreinigung:
- Protein G Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg