Monoclonal Antibody to RIG-I (Clone: ABM40B5)
Produktgrößen
25ug
£319,00
10-4102-25UG
100ug
£429,00
10-4102-100UG
Über dieses Produkt
- SKU:
- 10-4102
- Zusätzliche Namen:
- DDX58
- translate.label.attr.clone:
- ABM40B5
- Klonalität:
- Monoclonal
- Weitere Details:
- RIG-I or Probable ATP-dependent RNA helicase DDX58 or simply DDX58 is a RNA helicase enzyme with two isoforms (106 and 101 kDa). RIG-I belongs to the DEAD/H box family and is involved in several cellular responses including RNA binding and alteration of RNA secondary structure. RIG-1 acts as sensor of viral nucleic acids thus activating a cascade of antiviral responses including the induction of type I interferons and pro-inflammatory cytokines. Generally it remains as a monomer but upon activation by viral dsRNA it homomultimerizes and interacts with mitochondria antiviral signaling protein (MAVS/IPS1) which activating a cascade of reactions to produce specific interferon. RIG-1 is mostly expressed in vascular smooth cells.
- Format:
- Purified
- Gendetails:
- DDX58
- Host:
- Mouse
- Immunogen:
- A partial length recombinant human RIG-I protein (amino acids 1-220) was used as the immunogen for this antibody.
- Isotyp:
- Mouse IgG1 Kappa
- Aufreinigung:
- Protein G Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
