Monoclonal Antibody to Mouse CD196 (Clone: ABM40H1)
Produktgrößen
25ug
£319,00
10-4100-25UG
100ug
£429,00
10-4100-100UG
Über dieses Produkt
- SKU:
- 10-4100
- Zusätzliche Namen:
- C-C chemokine receptor type 6; C-C CKR-6; KY411
- translate.label.attr.clone:
- ABM40H1
- Klonalität:
- Monoclonal
- Weitere Details:
- CD196 displays a high degree of genetic homology between mouse and human. Moreover, in both species it is chromosomally segregated from the main chemokine receptor gene cluster. mCD196 is expressed by myeloid DCs (dendritic cells), mature B cells, subpopulations of memory/effector CD4+ and CD8+ T cells, but not plasmacytoid DCs or native T cells. mCD196 mediates their migration and function via stimulation with its ligand CCL20 (also known as macrophage inflammatory protein (MIP)-3alpha. mCD196 expression has been correlated with stage and prognosis in a variety of cancers including hepatocellular carcinoma, colorectal carcinoma, glioma, and non-small cell lung cancer. It is also believed to play a role in regulation of cancer progression.
- Format:
- Purified
- Gendetails:
- Ccr6
- Host:
- Rat
- Immunogen:
- Full length recombinant protein from mCD196 was used as the immunogen for this antibody.
- Isotyp:
- Rat IgG2a, Kappa
- Aufreinigung:
- Protein G Chromatography
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg