Monoclonal antibody to CD161 (clone: ABM27F5)
Produktgrößen
25ug
£319,00
10-4049-25UG
100ug
£375,00
10-4049-100UG
Über dieses Produkt
- SKU:
- 10-4049
- Zusätzliche Namen:
- Killer cell lectin-like receptor subfamily B member 1; C-type lectin domain family 5 member B; HNKR-P1a; NKR-P1A; Natural killer cell surface protein P1A; CD161
- translate.label.attr.clone:
- ABM27F5
- Klonalität:
- Monoclonal
- Weitere Details:
- CD161 is the human equivalent of mouse NK cell receptor P1A. It is a type II transmembrane glycoprotein with characteristics of the C-type lectin superfamily. The expression confines to lymphocytes found in human gut and liver, as well as blood, especially NK (natural killer) cells, Th17 (T helper 17) cells, and a population of unconventional T cells known as MAIT (mucosal-associated invariant T) cells. CD161 promotes T cell expansion and eventually has been identified as a marker of human IL-17-producing T cells. It plays a pivotal role in trans-endothelial migration and is also implicated in the pathogenesis of RA (rheumatoid arthritis) as well as graft-versus-host disease (GVHD).
- Format:
- Purified
- Gendetails:
- KLRB1
- Host:
- Mouse
- Immunogen:
- Full length recombinant protein of hCD161 was used as the immunogen for this antibody.
- Isotyp:
- Mouse IgG2b, Kappa
- Aufreinigung:
- Protein G Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg