Monoclonal Antibody to CLEC9A (Clone: ABM23H8)
Produktgrößen
25ug
£319,00
10-4020-25UG
100ug
£429,00
10-4020-100UG
Über dieses Produkt
- SKU:
- 10-4020
- Zusätzliche Namen:
- C-type lectin domain family 9 member A; CLEC9A
- translate.label.attr.clone:
- ABM23H8
- Klonalität:
- Monoclonal
- Weitere Details:
- CLEC9A is a C-type lectin receptor involved in the sensing and presentation of antigens derived from necrotic cells. It is expressed on the surface of the mouse and human dendritic cell subsets specialized for the uptake and processing of material from dead cells. CLEC9A is expressed at the cell surface as a glycosylated dimer and can mediate endocytosis, but not phagocytosis. It possesses a cytoplasmic immunoreceptor tyrosine-based activation-like motif that can recruit Syk kinase and can induce proinflammatory cytokine production. CLEC9A provides targeted recruitment of the adaptive immune system during infection and can also be utilized to enhance immune responses generated by vaccines.
- Format:
- Purified
- Gendetails:
- CLEC9A
- Host:
- Mouse
- Immunogen:
- A partial length recombinant protein ( a.a 15-218) of CLEC9A was used as the immunogen for this antibody.
- Isotyp:
- Mouse IgG1, Kappa
- Aufreinigung:
- Protein G Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg