Monoclonal Antibody to Mouse TLR9 (Clone: ABM4D70)
Produktgrößen
25ug
£319,00
10-3029-25UG
100ug
£429,00
10-3029-100UG
Über dieses Produkt
- SKU:
- 10-3029
- Zusätzliche Namen:
- Tlr9
- translate.label.attr.clone:
- ABM4D70
- Klonalität:
- Monoclonal
- Weitere Details:
- Mouse Toll-like receptor 9 (mTLR9) is an innate immune sensor for microbial DNA that erroneously responds to self DNA in autoimmune disease. TLR9 is normally expressed in endosomes/lysosomes where it is activated by pathogen-derived DNA. It has modulatory effect on the mucosal immune system, influence susceptibility to allergic sensitization to foods (22718261). TLR9 recognizes unmethylated CpG-containing DNA commonly found in bacteria. TLR9 signaling plays an important role in the development of robust protective immunity, proper recruitment and function of effector cells (lymphocytes and macrophages), and, ultimately, effective cryptococcal clearance from the infected lungs (20581055). It is involved in the pathogenesis of cardiovascular diseases, such as hypertension and heart failure.
- Format:
- Purified
- Gendetails:
- Tlr9
- Host:
- Rat
- Immunogen:
- A partial length recombinant mTLR9 protein (amino acids 602-860) was used as the immunogen for this antibody.
- Isotyp:
- Rat IgG2a Kappa
- Aufreinigung:
- Protein G Chromatography
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
