Monoclonal Antibody to TLR6 (Clone: ABM1B50)
Produktgrößen
25ug
£319,00
10-3002-25UG
100ug
£429,00
10-3002-100UG
Über dieses Produkt
- SKU:
- 10-3002
- Zusätzliche Namen:
- TLR6
- translate.label.attr.clone:
- ABM1B50
- Klonalität:
- Monoclonal
- Weitere Details:
- TLR6 (Toll-Like Receptors 6) is a member of the TLR (Toll-like receptor) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLR6 forms heterodimers with TLR1 and TLR2, which is the initial step in a cascade of events leading to significant innate immune responses, development of adaptive immunity to pathogens and protection from immune sequelae related to infection with these pathogens. TLR2 in co-operation with TLR6 trigger inflammatory responses via activation of NF-kappaB, which regulates the transcription of inflammatory molecules. TLR6 has emerged as the most potent activator for ZNPs (Zinc Oxide Nanoparticles)-induced inflammatory responses. Upon silencing, TLR6 significantly inhibited the pro-inflammatory cytokine levels, reactive nitrogen species generation and inducible nitric oxide synthase expression.
- Format:
- Purified
- Gendetails:
- TLR6
- Host:
- Mouse
- Immunogen:
- A partial length recombinant TLR6 protein (amino acids 280-512) was used as the immunogen for this antibody.
- Isotyp:
- Mouse IgG1 Kappa
- Aufreinigung:
- Protein G Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:anti-TLR6-mab-elisa.jpg
