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Antikörper

NALE™ Recombinant Human PD-1 rabbit monoclonal Antibody (Clone: ABMRR01) (No Azide Low Endotoxin)

Produktgrößen
100ug
£496,00
10-2001-NALE-100UG
Über dieses Produkt
SKU:
10-2001-NALE
Zusätzliche Namen:
PDCD1; PD1; CD279
translate.label.attr.clone:
ABMRR01
Klonalität:
Monoclonal
Weitere Details:
PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.
Format:
Azide Free;Purified
Gendetails:
PDCD1
Isotyp:
Rabbit IgG
Aufreinigung:
Protein A Chromatography
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody
  • Datenblatt des Herstellers:1.jpg
Fig-2: Cell surface flow analysis of Rabbit recombinant h PD-1 antibody in CHO-PD1 transfected cell line using 0.2 µg/10^6 cells of Rabbit recombinant hPD-1 antibody (Clone: ABMRR01). Green represent CHO/K1 cells and red represent Rabbit recombinant hPD-1 antibody. Goat anti rabbit PE conjugate was used as secondary antibody.
Fig-3: Western blot analysis of Rabbit recombinant hPD-1 antibody. Anti-Rabbit recombinant hPD-1 antibody was tested at 1 µg/ml in Jurkat cell lysate
Fig-4: Functional activity of NALE™ Recombinant hPD-1 rabbit monoclonal antibody was evaluated using the Jurkat-PD-1/NFAT cell- and CHO/PD-L1 inducer cell-based assay system; in which the PD-1 antibody interferes with the binding between PD-1 and PD-L1 in a dose response manner; leading to the NFAT reporter gene induction.
Fig-4: Functional activity of NALE™ Recombinant hPD-1 rabbit monoclonal antibody was evaluated using the Jurkat-PD-1/NFAT cell- and CHO/PD-L1 inducer cell-based assay system; in which the PD-1 antibody interferes with the binding between PD-1 and PD-L1 in a dose response manner; leading to the NFAT reporter gene induction.