In vivo Grade Recombinant Anti-mouse CD28 Monoclonal Antibody, Syrian Hamster IgG2 (Clone: 37.51)
Produktgrößen
1 mg
£225,00
YR0385-1MG
5 mg
£659,00
YR0385-5MG
25 mg
£1617,00
YR0385-25MG
Über dieses Produkt
- SKU:
- YR0385
- Anwendung:
- Block/Inhibit/Neutralise, Cell-based/Functional Assay, ELISA, Flow Cytometry
- Klonalität:
- Monoclonal
- Weitere Details:
- The in vivo grade recombinant hamster monoclonal antibody (clone: 37.51) specifically binds to the mouse CD28 protein. CD28 is a critical costimulatory receptor belonging to the immunoglobulin superfamily. Upon binding to its ligands CD80 (B7-1) and CD86 (B7-2)-expressed on antigen-presenting cells (APCs)-CD28 triggers intracellular signaling cascades that promote T cell proliferation, cytokine production, and the survival of activated T cells. Dysregulation of CD28 signaling is linked to autoimmune diseases, immune deficiency, and impaired antitumor immunity, making it a central target for studying immune activation and modulation in murine models.
- Formulierung:
- Purified from cell culture supernatant in an animal-free facility
- Isotyp:
- IgG2
- Molekulargewicht:
- 150kDa
- Reinheit:
- >95%
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Avoid freeze/thaw cycles., -70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- ABclonal Technology
- Typ:
- Antibody: Biosimilar Antibody
- Datenblatt des Herstellers:YR0385