Recombinant Human Pyruvate kinase PKM/PKM protein
Produktgrößen
10 ug
£159,00
RP03215LQ-10UG
50 ug
£313,00
RP03215LQ-50UG
Über dieses Produkt
- SKU:
- RP03215LQ
- Zusätzliche Namen:
- CTHBP|OIP-3|Pyruvate kinase PKM|THBP1
- Weitere Details:
- Pyruvate kinase isoform M2 (PKM2) is a member of the pyruvate kinase (PK) family, a pivotal glycolytic enzyme that is consistently changed during tumorigenesis. PKM2 is expressed in some differentiated tissues, such as lung, fat tissue, retina, and pancreatic islets. As the rate-controlling enzyme in glycolysis, PKM2, has also been found to be expressed in embryonic, proliferating, and tumor cells, and it has been considered to be crucial for the metabolism and growth of tumor cells. Recent studies have shown that PKM2 promotes cell proliferation and suppresses cell apoptosis in various tumors. In addition, it has been reported that the PKM2 knockdown affects the Akt and ERK protein kinases.
- Formulierung:
- Recombinant Human PKM2 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Ser2-Pro531) of human PKM2 (Accession #NP_002645.3) fused with His tag at the N-
- Immunogen:
- Ser2-Pro531
- Molekulargewicht:
- 60 kda
- Reinheit:
- ≥95%
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- -70[o]C Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- ABclonal Technology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
- Datenblatt des Herstellers:RP03215LQ