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Proteine und Peptide

Recombinant Mouse/Rat Flt4 ligand/VEGF-C Protein

Produktgrößen
10 ug
£163,00
RP02804-10UG
20 ug
£223,00
RP02804-20UG
50 ug
£336,00
RP02804-50UG
100 ug
£508,00
RP02804-100UG
500 ug
£1478,00
RP02804-500UG
1000 ug
£2335,00
RP02804-1000UG
Über dieses Produkt
SKU:
RP02804
Zusätzliche Namen:
VEGF-C|VEGFC,Flt4-L,LMPH1D,VRP
Weitere Details:
Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotein, as a ligand for two receptors, VEGFR-3 (Flt4), and VEGFR-2. VEGF-C may function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis. VEGF-C protein is over-expressed in various human cancers including breast cancer and prostate cancer. VEGF-C/VEGFR-3 axis, through different signaling pathways, plays a critical role in cancer progression by regulating different cellular functions, such as invasion, proliferation, and resistance to chemotherapy. Thus, targeting the VEGF-C/VEGFR-3 axis may be therapeutically significant for certain types of tumors.
Formulierung:
Recombinant Mouse/Rat VEGF-C Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala108-Arg223) of mouse/rat VEGF-C (Accession #NP_033532.1) fused wit
Immunogen:
Ala108-Arg223
Molekulargewicht:
20-25 kDa
Physischer Zustand:
Lyophilized
Reinheit:
≥95%
Sequenz:
AHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGAATNTFFKPPCVSVYRCGGCCNSEGLQCMNTSTGYLSKTLFEITVPLSQGPKPVTISFANHTSCRCMSKLDVYRQVHSIIRR
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Hersteller:
ABclonal Technology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins