Recombinant Human Annexin A2/ANXA2 Protein
Produktgrößen
10 ug
£133,00
RP02731-10UG
20 ug
£181,00
RP02731-20UG
50 ug
£240,00
RP02731-50UG
100 ug
£353,00
RP02731-100UG
500 ug
£1336,00
RP02731-500UG
1000 ug
£1574,00
RP02731-1000UG
Über dieses Produkt
- SKU:
- RP02731
- Zusätzliche Namen:
- Annexin A2|Annexin II|ANX2|ANX2L4|ANXA2|CAL1H|Chromobindin-8|LIP2PAP-IV|Lipocortin II|LPC2D|LPC2DP36|p36|PAP-IV
- Weitere Details:
- ANXA2, highly expressed in invasive breast cancer cells, is closely related with poor prognosis, and acts as a molecular switch to EGFR activation. ANXA2 expression is inversely correlated with cell sensitivity to gefitinib. Knockdown of ANXA2 expression in MDA-MB-231 cells increased the gefitinib induced cell death. When ANXA2 was overexpressed in MCF7 cells, the gefitinib induced cell death was decreased. Furthermore, the phosphorylation of ANXA2 at Tyr23 is negatively correlated with the sensitivity of TNBC to gefitinib.
- Formulierung:
- Recombinant Human Annexin A2/ANXA2 Protein is produced by E. coli expression system. The target protein is expressed with sequence Ser2-Asp339. of Human Annexin A2/ANXA2 (Accession #) fused with His t
- Immunogen:
- Ser2-Asp339
- Molekulargewicht:
- 39 kDa
- Reinheit:
- ≥95%
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Hersteller:
- ABclonal Technology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:RP02731