Biotinylated Recombinant Human Notch 2 Protein
Produktgrößen
100 ug
£657,00
RP02462B-100UG
500 ug
£2555,00
RP02462B-500UG
Über dieses Produkt
- SKU:
- RP02462B
- Zusätzliche Namen:
- NOTCH2,AGS2,HJCYS,hN2,notch 2
- Konjugat:
- Biotin
- Weitere Details:
- Human Notch-2 is a 300 kDa type I transmembrane glycoprotein that is one of four human Notch homologues involved in developmental processes. Although Notch proteins are structurally and functionally similar, deletion of either Notch-1 or Notch-2 is lethal, showing that not all functions overlap.Notch-2 functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus.
- Formulierung:
- Biotinylated Recombinant Human Notch 2 Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Leu26-Gln530) of Human Notch 2 fused with a His tag and Avi tag
- Immunogen:
- Leu26-Gln530
- Molekulargewicht:
- 70-80 kDa
- Physischer Zustand:
- Lyophilized
- Reinheit:
- ≥ 95 % as determined by Tris-Bis PAGE;≥ 95 %
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Hersteller:
- ABclonal Technology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
- Datenblatt des Herstellers:RP02462B