Recombinant Mouse IL-31 Protein
Produktgrößen
10 ug
£145,00
RP01835-10UG
20 ug
£193,00
RP01835-20UG
50 ug
£288,00
RP01835-50UG
100 ug
£431,00
RP01835-100UG
500 ug
£1240,00
RP01835-500UG
1000 ug
£1954,00
RP01835-1000UG
Über dieses Produkt
- SKU:
- RP01835
- Zusätzliche Namen:
- 1700013B14Rik|IL-31|Il-31; interleukin 31|il31
- Weitere Details:
- IL-31 is an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens. Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. It has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis. May function in skin immunity. IL-31 is produced by a variety of cells, namely type 2 helper (TH2) T-cells. IL-31 sends signals through a receptor complex made of IL-31RA and oncostatin M receptor B Beta (OSMRB Beta) expressed in immune and epithelial cells. These signals activate three pathways: ERK1/2 MAP kinase, PI3K/AKT, and JAK1/2 signaling pathways.
- Formulierung:
- Recombinant Mouse IL-31 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Thr24-Cys163) of mouse IL-31 (Accession #NP_083870.1) fused with a 6xHis t
- Immunogen:
- Thr24-Cys163
- Molekulargewicht:
- 15-35 kDa
- Physischer Zustand:
- Lyophilized
- Reinheit:
- ≥90%
- Sequenz:
- TCSLSFGAPISKEDLRTTIDLLKQESQDLYNNYSIKQASGMSADESIQLPCFSLDREALTNISVIIAHLEKVKVLSENTVDTSWVIRWLTNISCFNPLNLNISVPGNTDESYDCKVFVLTVLKQFSNCMAELQAKDNTTC
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Hersteller:
- ABclonal Technology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:RP01835