Recombinant Mouse IL1RL1/ST2 Protein
Produktgrößen
10 ug
£133,00
RP01673-10UG
20 ug
£181,00
RP01673-20UG
50 ug
£240,00
RP01673-50UG
100 ug
£353,00
RP01673-100UG
500 ug
£1002,00
RP01673-500UG
1000 ug
£1574,00
RP01673-1000UG
Über dieses Produkt
- SKU:
- RP01673
- Zusätzliche Namen:
- DER4|Fit-1|Ly84|St2|St2-rs1; IL1RL1|ST2L|T1|T1/ST2
- Weitere Details:
- IL-1 receptor-like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage proinflammatory function. IL33 is a specific ligand of ST2L and induces the production of Th2 cytokines.
- Formulierung:
- Recombinant Mouse IL1RL1/ST2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser27-Ala332) of mouse IL1RL1 (Accession #NP_001020773.1) fused with
- Immunogen:
- Ser27-Arg332
- Molekulargewicht:
- 75-100 kDa
- Physischer Zustand:
- Lyophilized
- Reinheit:
- ≥90%
- Sequenz:
- SKSSWGLENEALIVRCPQRGRSTYPVEWYYSDTNESIPTQKRNRIFVSRDRLKFLPARVEDSGIYACVIRSPNLNKTGYLNVTIHKKPPSCNIPDYLMYSTVRGSDKNFKITCPTIDLYNWTAPVQWFKNCKALQEPRFRAHRSYLFIDNVTHDDEGDYTCQFTHAENGTNYIVTATRSFTVEEKGFSMFPVITNPPYNHTMEVEIGKPASIACSACFGKGSHFLADVLWQINKTVVGNFGEARIQEEEGRNESSSNDMDCLTSVLRITGVTEKDLSLEYDCLALNLHGMIRHTIRLRRKQPIDHR
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Hersteller:
- ABclonal Technology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:RP01673