Recombinant Mouse IL-13 Protein
Produktgrößen
10 ug
£163,00
RP01596S-10UG
20 ug
£223,00
RP01596S-20UG
50 ug
£336,00
RP01596S-50UG
100 ug
£508,00
RP01596S-100UG
500 ug
£1478,00
RP01596S-500UG
1000 ug
£2335,00
RP01596S-1000UG
Über dieses Produkt
- SKU:
- RP01596S
- Zusätzliche Namen:
- Interleukin-13, IL-13, T-cell activation protein P600, Il13, Il-13
- Weitere Details:
- Mouse interleukin 13 (mIL-13) is a pleiotropic cytokine produced by activated Th2 cells. IL-13 induces B cell proliferation and immunoglobin production. It contains a four helical bundle with two internal disulfide bonds. Mouse IL13 shares 58% sequence identity with human protein and exhibits cross-species activity. IL13 signals via receptor IL13R (type2, IL4R) and activates STAT-6. IL13 initially binds IL-13RA Alpha1 with low affinity and triggers association of IL4R A Alpha , generating a high affinity heterodimeric receptor IL13R and eliciting downstream signals. IL13 also binds IL-13RA Alpha2 with high affinity, which plays a role in a negative feedback system of IL13 signaling. IL13 is an important mediator of allergic inflammation and disease.
- Formulierung:
- Recombinant Mouse IL-13 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly21-Phe131) of Mouse IL-13 (Accession #P20109) fused with a His at the N
- Immunogen:
- Gly21-Phe131
- Molekulargewicht:
- 15-35 kDa
- Physischer Zustand:
- Lyophilized
- Reinheit:
- ≥90%
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Hersteller:
- ABclonal Technology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:RP01596S