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Proteine und Peptide

Recombinant Mouse TNFRSF9/4-1BB/CD137 Protein

Produktgrößen
10 ug
£127,00
RP01560-10UG
20 ug
£175,00
RP01560-20UG
50 ug
£240,00
RP01560-50UG
100 ug
£336,00
RP01560-100UG
500 ug
£1002,00
RP01560-500UG
1000 ug
£1574,00
RP01560-1000UG
Über dieses Produkt
SKU:
RP01560
Zusätzliche Namen:
4-1BB ,CD137 ,CDw137 ,ILA,TNFRSF9,4-1BB ,CD137 ,CDw137 ,ILA,TNFRSF9
Weitere Details:
CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necrosis factor (TNF) receptor superfamily. It is expressed mainly on activated CD4+ and CD8+ T cells, and binds to a high-affinity ligand (4-1BBL) expressed on several antigen-presenting cells such as macrophages and activated B cells. Upon ligand binding, 4-1BB is associated with the tumor necrosis factor receptor-associated factors (TRAFs), the adaptor protein which mediates downstream signaling events including the activation of NF-kappaB and cytokine production. 4-1BB signaling either by binding to 4-1BBL or by antibody ligation delivers signals for T-cell activation and growth, as well as monocyte proliferation and B-cell survival, and plays an important role in the amplification of T cell-mediated immune responses.
Formulierung:
Recombinant Mouse TNFRSF9/4-1BB/CD137 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val24-Leu211) of mouse TNFRSF9/4-1BB/CD137 (Accession #NP_00
Immunogen:
Val24-Leu211
Molekulargewicht:
60-70 kDa
Physischer Zustand:
Lyophilized
Reinheit:
≥95%
Sequenz:
VQNSCDNCQPGTFCRKYNPVCKSCPPSTFSSIGGQPNCNICRVCAGYFRFKKFCSSTHNAECECIEGFHCLGPQCTRCEKDCRPGQELTKQGCKTCSLGTFNDQNGTGVCRPWTNCSLDGRSVLKTGTTEKDVVCGPPVVSFSPSTTISVTPEGGPAFKKTTGAAQEEDACSCRCPQEEEGGGGGYEL
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Hersteller:
ABclonal Technology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins