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Proteine und Peptide

Recombinant Human LR3-IGF-1(E51R) Protein

Produktgrößen
50 ug
£115,00
RP00825-50UG
100 ug
£145,00
RP00825-100UG
500 ug
£354,00
RP00825-500UG
1000 ug
£509,00
RP00825-1000UG
Über dieses Produkt
SKU:
RP00825
Zusätzliche Namen:
IGF1, IBP1, IGF-1,Insulin-like growth factor 1, Insulin-like growth factor I, IGF-I, Mechano growth factor, MGF, Somatomedin-C
Weitere Details:
Long R3 IGF-1 (LR3 IGF-1) is a synthetic analog of IGF-1 that is generated by modifying the AA sequence for mature human IGF-1. These modifications include the substitution of an Arg for Glu at position three of the mature IGF-1 sequence and the addition of a thirteen aa N-terminal extension, which is derived from methionyl porcine Growth Hormone. These aa changes generate a protein that is still capable of binding to IGF-1 and Insulin receptors, but shows considerably lower affinity binding to IGFBPs compared to wild-type IGF-1. As a result, LR3 IGF-1 has an increased half-life and displays increased biological potency compared to IGF-1.
Formulierung:
Recombinant Human LR3-IGF-1(E51R) Protein is produced by E. coli expression system. The target protein is expressed with sequence (Gly49-Ala118) of human IGF-1 (Accession #P05019) with the substitutio
Immunogen:
MFPAMPLSSLFVNGly49-Ala118 (Glu51Arg)
Molekulargewicht:
10-15 kDa
Physischer Zustand:
Lyophilized
Reinheit:
≥95%
Sequenz:
MFPAMPLSSLFVNGPRTLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Hersteller:
ABclonal Technology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins