Recombinant Human PBEF/Visfatin/NAMPT Protein
Produktgrößen
10 ug
£133,00
RP00724-10UG
20 ug
£181,00
RP00724-20UG
50 ug
£240,00
RP00724-50UG
100 ug
£353,00
RP00724-100UG
500 ug
£1240,00
RP00724-500UG
1000 ug
£1954,00
RP00724-1000UG
Über dieses Produkt
- SKU:
- RP00724
- Zusätzliche Namen:
- NAMPT,1110035O14Rik,PBEF,PBEF1,VF,VISFATIN
- Weitere Details:
- Pre-B cell colony enhancing factor (PBEF) was originally identified as a cytokine that potentiated the clonalexpansion and differentiation of pre-B cells, but it is also acknowledged to be the ubiquitous intracellularenzyme nicotinamide phosphoribosyltranferase (NAMPT) and the adipokine " visfatin " . PBEF is constitutivelyexpressed in the fetal membranes where its greatest expression is in the amnion. It has intracellular andextracellular forms. Most of the intracellular functions of PBEF are due to its role as a Nampt which can induceangiogenesis through upregulation of VEGF and VEGFR and secretion of MCP-1. Extracellular PBEF has beenshown to increase inflammatory cytokines, such as TNF- A Alpha , IL-1 B Beta , IL-16, and TGF- B Beta 1. PBEF also increases theproduction of IL-6, TNF- A Alpha , and IL-1 B Beta in CD14+ monocyctes, macrophages, and dendritic cells, enhances theeffectiveness of T cells.
- Formulierung:
- Recombinant Human PBEF/Visfatin/NAMPT Protein is produced by E. coli expression system. The target protein is expressed with sequence (Asn2-His491) of human Visfatin/Nampt (Accession #P43490) fused wi
- Immunogen:
- Asn2-His491
- Molekulargewicht:
- 60-65 kDa
- Physischer Zustand:
- Lyophilized
- Reinheit:
- ≥95%
- Sequenz:
- NPAAEAEFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKTENSKLRKVKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIELEAAHH
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Hersteller:
- ABclonal Technology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:RP00724
