Recombinant Human Nectin-4/PVRL4 Protein
Produktgrößen
10 ug
£145,00
RP00642-10UG
20 ug
£181,00
RP00642-20UG
50 ug
£288,00
RP00642-50UG
100 ug
£354,00
RP00642-100UG
500 ug
£1002,00
RP00642-500UG
1000 ug
£1574,00
RP00642-1000UG
Über dieses Produkt
- SKU:
- RP00642
- Zusätzliche Namen:
- NECTIN4, LNIR, PRR4, PVRL4, Nectin-4, Processed poliovirus receptor-related protein 4
- Weitere Details:
- Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamilyproteins. It contains two Ig-like C2-type domains and one Ig-like V-type domain. PVRL4 seems to be involved incell adhesion through trans-homophilic and -heterophilic interactions, the latter including specificallyinteractions with nectin-1. It does not act as receptor for alpha-herpesvirus entry into cells. It is predominantlyexpressed in placenta, the embryo and breast carcinoma. But it is not detected in normal breast epithelium.The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17.Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomalrecessive disorder.
- Formulierung:
- Recombinant Human Nectin-4/PVRL4 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Ser349) of Human Nectin-4/PVRL4 (Accession #NP_112178.2) fus
- Immunogen:
- Met1-Ser349
- Molekulargewicht:
- 35-45kDa
- Physischer Zustand:
- Lyophilized
- Reinheit:
- ≥95%
- Sequenz:
- GELETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVSASVV
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Hersteller:
- ABclonal Technology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:RP00642
