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Proteine und Peptide

Recombinant Human MCAM/CD146 Protein

Produktgrößen
50 ug
£288,00
RP00101-50UG
100 ug
£431,00
RP00101-100UG
500 ug
£1431,00
RP00101-500UG
1000 ug
£2258,00
RP00101-1000UG
Über dieses Produkt
SKU:
RP00101
Zusätzliche Namen:
CD146, MUC18,MCAM, CD146, cell surface glycoprotein MUC18,MUC18
Weitere Details:
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
Formulierung:
Recombinant Human MCAM/CD146 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val24-Gly559) of human CD146/MCAM (Accession #NP_006491.2) fused with
Immunogen:
Val24-Gly559
Molekulargewicht:
90-120 kDa
Physischer Zustand:
Lyophilized
Reinheit:
≥95%
Sequenz:
VPGEAEQPAPELVEVEVGSTALLKCGLSQSQGNLSHVDWFSVHKEKRTLIFRVRQGQGQSEPGEYEQRLSLQDRGATLALTQVTPQDERIFLCQGKRPRSQEYRIQLRVYKAPEEPNIQVNPLGIPVNSKEPEEVATCVGRNGYPIPQVIWYKNGRPLKEEKNRVHIQSSQTVESSGLYTLQSILKAQLVKEDKDAQFYCELNYRLPSGNHMKESREVTVPVFYPTEKVWLEVEPVGMLKEGDRVEIRCLADGNPPPHFSISKQNPSTREAEEETTNDNGVLVLEPARKEHSGRYECQGLDLDTMISLLSEPQELLVNYVSDVRVSPAAPERQEGSSLTLTCEAESSQDLEFQWLREETGQVLERGPVLQLHDLKREAGGGYRCVASVPSIPGLNRTQLVNVAIFGPPWMAFKERKVWVKENMVLNLSCEASGHPRPTISWNVNGTASEQDQDPQRVLSTLNVLVTPELLETGVECTASNDLGKNTSILFLELVNLTTLTPDSNTTTGLSTSTASPHTRANSTSTERKLPEPESRG
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Hersteller:
ABclonal Technology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins