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Antikörper

Rabbit anti-Human/Mouse/Rat/Monkey/Porcine/Bovine TGF beta 1 monoclonal antibody

Produktgrößen
100 ug
£438,00
RMK0522-100UG
200 ug
£599,00
RMK0522-200UG
500 ug
£1503,00
RMK0522-500UG
1000 ug
£2741,00
RMK0522-1000UG
Über dieses Produkt
SKU:
RMK0522
Zusätzliche Namen:
CED|DPD1|IBDIMDE|LAP|TGF-beta1|TGFB|TGFbeta
Anwendung:
Detection/Quantitation, ELISA
Klonalität:
Monoclonal
Weitere Details:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
Formulierung:
Supplied as a 0.2 um filtered solution in PBS with 0.05% Proclin 300, pH 7.4.
Immunogen:
Recombinant human TGF beta 1 protein
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Versandbedingungen:
Dry Ice
Lagerbedingungen:
-20[o]C
Hersteller:
ABclonal Technology
Typ:
Antibody: Monoclonal Antibody