Rabbit anti-Human TSLP monoclonal antibody
Produktgrößen
100 ug
£438,00
RMK0229-100UG
200 ug
£599,00
RMK0229-200UG
500 ug
£1503,00
RMK0229-500UG
1000 ug
£2741,00
RMK0229-1000UG
Über dieses Produkt
- SKU:
- RMK0229
- Anwendung:
- Detection/Quantitation
- Klonalität:
- Monoclonal
- Weitere Details:
- This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. In addition, the shorter (predominant) isoform is an antimicrobial protein, displaying antibacterial and antifungal activity against B. cereus, E. coli, E. faecalis, S. mitis, S. epidermidis, and C. albicans. Alternative splicing of this gene results in multiple transcript variants.
- Formulierung:
- Supplied as a 0.2 um filtered solution in PBS with 0.05% Proclin 300, pH 7.4.
- Immunogen:
- Recombinant human TSLP Protein
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ABclonal Technology
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:RMK0229