Rabbit anti-Human P-cadherin/CDH3 monoclonal antibody
Produktgrößen
100 ug
£438,00
RMK0186-100UG
500 ug
£1503,00
RMK0186-500UG
1000 ug
£2741,00
RMK0186-1000UG
Über dieses Produkt
- SKU:
- RMK0186
- Zusätzliche Namen:
- CDHP|HJMD|PCAD
- Anwendung:
- Detection/Quantitation, ELISA
- Klonalität:
- Monoclonal
- Weitere Details:
- This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS).
- Formulierung:
- Supplied as a 0.2um filtered solution in PBS with 0.05%ProClin 300,PH 7.4.
- Immunogen:
- Recombinant Human P-cadherin/CDH3
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ABclonal Technology
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:RMK0186