Rabbit anti-Human TNF RII monoclonal antibody(DET)
Produktgrößen
100 ug
£409,00
RMK0086-100UG
200 ug
£599,00
RMK0086-200UG
500 ug
£1503,00
RMK0086-500UG
1000 ug
£2551,00
RMK0086-1000UG
Über dieses Produkt
- SKU:
- RMK0086
- Zusätzliche Namen:
- CD120b|p75|p75TNFR|TBPII|TNF-R-II|TNF-R75|TNFBR|TNFR1B|TNFR2|TNFR80
- Anwendung:
- ELISA
- Klonalität:
- Monoclonal
- Weitere Details:
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
- Formulierung:
- Supplied as a 0.2 um filtered solution in PBS with 0.05% Proclin 300, pH 7.4.
- Immunogen:
- Recombinant human TNF RII
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ABclonal Technology
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:RMK0086