Rabbit anti-Human cTnI monoclonal antibody(DET)
Produktgrößen
100 ug
£409,00
RMK0029-100UG
200 ug
£599,00
RMK0029-200UG
500 ug
£1503,00
RMK0029-500UG
1000 ug
£2551,00
RMK0029-1000UG
Über dieses Produkt
- SKU:
- RMK0029
- Zusätzliche Namen:
- CMD1FF|CMD2A|CMH7|cTnI|RCM1|TNNC1
- Anwendung:
- CLIA, Detection/Quantitation
- Klonalität:
- Monoclonal
- Weitere Details:
- Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). Troponin I is useful in making a diagnosis of heart failure, and of ischemic heart disease. An elevated level of troponin is also now used as indicator of acute myocardial injury in patients hospitalized with moderate/severe Coronavirus Disease 2019 (COVID-19). Such elevation has also been associated with higher risk of mortality in cardiovascular disease patients hospitalized due to COVID-19.
- Formulierung:
- Supplied as a 0.2 um filtered solution in PBS with 0.05% Proclin 300, pH 7.3.
- Immunogen:
- Synthetic peptide corresponding to human cTnI
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ABclonal Technology
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:RMK0029