Rabbit anti-Human uPAR monoclonal antibody
Produktgrößen
100 ug
£409,00
RM18034-100UG
200 ug
£599,00
RM18034-200UG
500 ug
£1503,00
RM18034-500UG
1000 ug
£2551,00
RM18034-1000UG
Über dieses Produkt
- SKU:
- RM18034
- Zusätzliche Namen:
- CD87|U-PAR|UPAR|URKR
- Anwendung:
- ELISA
- Klonalität:
- Monoclonal
- Weitere Details:
- This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
- Formulierung:
- Supplied as a 0.2 um filtered solution in PBS with 0.05% Proclin 300, pH 7.4.
- Immunogen:
- Recombinant Human uPAR
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ABclonal Technology
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:RM18034