Rabbit anti-Human TNFR1 monoclonal antibody
Produktgrößen
100 ug
£438,00
RM17949-100UG
500 ug
£1503,00
RM17949-500UG
1000 ug
£2521,00
RM17949-1000UG
Über dieses Produkt
- SKU:
- RM17949
- Zusätzliche Namen:
- CD120a|FPF|p55|p55-R|p60|TBP1|TNF-R|TNF-R-I|TNF-R55|TNFAR|TNFR1|TNFR55|TNFR60
- Anwendung:
- Detection/Quantitation, ELISA
- Klonalität:
- Monoclonal
- Weitere Details:
- This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mutations in this gene underlie tumor necrosis factor receptor-associated periodic syndrome (TRAPS), characterized by fever, abdominal pain and other features. Mutations in this gene may also be associated with multiple sclerosis in human patients.
- Formulierung:
- Supplied as a 0.2um filtered solution in PBS with 0.05%ProClin 300,PH 7.4.
- Immunogen:
- Recombinant Human TNFR1 Protein
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ABclonal Technology
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:RM17949