Rabbit anti-Human TNF-alpha monoclonal antibody
Produktgrößen
100 ug
£438,00
RM17748-100UG
1000 ug
£2741,00
RM17748-1000UG
Über dieses Produkt
- SKU:
- RM17748
- Zusätzliche Namen:
- DIF|TNF-alpha|TNFA|TNFSF2|TNLG1F
- Anwendung:
- CLIA
- Klonalität:
- Monoclonal
- Weitere Details:
- This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, psoriasis, rheumatoid arthritis ankylosing spondylitis, tuberculosis, autosomal dominant polycystic kidney disease, and cancer. Mutations in this gene affect susceptibility to cerebral malaria, septic shock, and Alzheimer disease. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
- Formulierung:
- Supplied as a 0.2um filtered solution in PBS with 0.05% Proclin300, PH 7.4.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human TNF-alpha Protein
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ABclonal Technology
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:RM17748