Rabbit anti-Human IFN-A Alpha monoclonal antibody (DET)
Produktgrößen
100 ug
£438,00
RM17742-100UG
1000 ug
£2741,00
RM17742-1000UG
Über dieses Produkt
- SKU:
- RM17742
- Zusätzliche Namen:
- IFN-alpha-2|IFN-alphaA|IFNA|IFNA2B|leIF A
- Anwendung:
- CLIA, Detection/Quantitation, ELISA
- Klonalität:
- Monoclonal
- Weitere Details:
- This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. The encoded protein is effective in reducing the symptoms and duration of the common cold and in treating many types of cancer, including some hematological malignancies and solid tumors. A deficiency of type I interferon in the blood is thought to be a hallmark of severe COVID-19 and may provide a rationale for a combined therapeutic approach.
- Formulierung:
- Supplied as a 0.2um filtered solution in PBS with 0.05% Proclin300, PH 7.4.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 24-188 of human IFN-A Alpha (NP_000596.2).
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ABclonal Technology
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:RM17742