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Antikörper

Rabbit anti-Mouse IL-6(DET)

Produktgrößen
100 ug
£409,00
RM17710-100UG
200 ug
£599,00
RM17710-200UG
500 ug
£1503,00
RM17710-500UG
1000 ug
£2551,00
RM17710-1000UG
Über dieses Produkt
SKU:
RM17710
Zusätzliche Namen:
BSF-2|BSF2|CDF|HGF|HSF|IFN-beta-2|IFNB2|IL-6|IL6
Anwendung:
ELISA
Weitere Details:
Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation leads to the regulation of the immune response, acute-phase reactions and hematopoiesis. The interaction with membrane-bound IL6R and IL6ST stimulates "classic signaling", the restricted expression of the IL6R limits classic IL6 signaling to only a few tissues such as the liver and some cells of the immune system. Whereas the binding of IL6 and soluble IL6R to IL6ST stimulates "trans-signaling". Alternatively, "cluster signaling" occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.
Formulierung:
Supplied as a 0.2 um filtered solution in PBS with 0.05% Proclin 300, pH 7.4.
Immunogen:
Recombinant mouse IL-6 Protein
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Mouse
Versandbedingungen:
Dry Ice
Lagerbedingungen:
-20[o]C
Hersteller:
ABclonal Technology
Typ:
Antibody
  • Datenblatt des Herstellers:RM17710