Rabbit anti-Human IL-10 monoclonal antibody (CAP)
Produktgrößen
100 ug
£409,00
RM17643-100UG
200 ug
£599,00
RM17643-200UG
500 ug
£1503,00
RM17643-500UG
1000 ug
£2551,00
RM17643-1000UG
Über dieses Produkt
- SKU:
- RM17643
- Zusätzliche Namen:
- CSIF|GVHDS|IL-10|IL10A|TGIF
- Anwendung:
- CLIA, Detection/Quantitation
- Klonalität:
- Monoclonal
- Weitere Details:
- The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.
- Formulierung:
- Supplied as a 0.2um filtered solution in PBS with 0.05% Proclin300, PH 7.4.
- Immunogen:
- Recombinant Human IL-10 Protein Ser19-Asn178 Accession #P22301
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ABclonal Technology
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:RM17643