Phospho-p38 MAPK-T180 Rabbit monoclonal antibody
Produktgrößen
5 ul
£ POA
AP1508-5UL
20 ul
£163,00
AP1508-20UL
100 ul
£342,00
AP1508-100UL
500 ul
£1532,00
AP1508-500UL
1000 ul
£2704,00
AP1508-1000UL
Über dieses Produkt
- SKU:
- AP1508
- Zusätzliche Namen:
- CSBP|CSBP1|CSBP2|CSPB1|EXIP|MAPK14|Mxi2|p38|p38 MAPK|p38ALPHA|Phospho-p38 MAPK-T180|PRKM14|PRKM15|RK|SAPK2A
- Anwendung:
- ELISA, IHC-Paraffin, Western Blot
- Klonalität:
- Monoclonal
- Weitere Details:
- The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
- Formulierung:
- Phospho T180
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide. This information is considered to be commercially sensitive.
- Isotyp:
- IgG
- Molekulargewicht:
- 40kda
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Sequenz:
- DEMTGY
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- ABclonal Technology
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:AP1508