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Antikörper

TMPRSS2 Rabbit monoclonal antibody

Produktgrößen
5 ul
£ POA
A9126-5UL
20 ul
£163,00
A9126-20UL
100 ul
£342,00
A9126-100UL
500 ul
£1532,00
A9126-500UL
1000 ul
£2704,00
A9126-1000UL
Über dieses Produkt
SKU:
A9126
Zusätzliche Namen:
PRSS10|TMPRSS2
Anwendung:
ELISA, IHC-Paraffin, Western Blot
Klonalität:
Monoclonal
Weitere Details:
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. This protein also facilitates entry of viruses into host cells by proteolytically cleaving and activating viral envelope glycoproteins. Viruses found to use this protein for cell entry include Influenza virus and the human coronaviruses HCoV-229E, MERS-CoV, SARS-CoV and SARS-CoV-2 (COVID-19 virus). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Formulierung:
Unmodified
Host:
Rabbit
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Isotyp:
IgG
Molekulargewicht:
54kDa
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Sequenz:
MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAAL
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
ABclonal Technology
Typ:
Antibody: Monoclonal Antibody
  • Datenblatt des Herstellers:A9126
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