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Antikörper

GLUD1 Rabbit polyclonal antibody

Produktgrößen
20 ul
£152,00
A7631-20UL
100 ul
£336,00
A7631-100UL
500 ul
£1258,00
A7631-500UL
1000 ul
£2228,00
A7631-1000UL
Über dieses Produkt
SKU:
A7631
Zusätzliche Namen:
GDH|GDH1|GLUD|GLUD1|hGDH1
Anwendung:
ELISA, IHC-Paraffin, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Klonalität:
Polyclonal
Weitere Details:
This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.
Formulierung:
Unmodified
Host:
Rabbit
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Isotyp:
IgG
Molekulargewicht:
52kDa
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Sequenz:
SEAVADREDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYAS
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
ABclonal Technology
Typ:
Antibody: Polyclonal Antibody
  • Datenblatt des Herstellers:A7631