FITC Rabbit anti-Human/Monkey TCR G Gamma/D Delta monoclonal antibody
Produktgrößen
10 tests
£ POA
A28422-10TESTS
100 tests
£199,00
A28422-100TESTS
2 x 100 tests
£324,00
A28422-2X100TESTS
5 x 100 tests
£687,00
A28422-5X100TESTS
Über dieses Produkt
- SKU:
- A28422
- Zusätzliche Namen:
- TCRD|TCRDV1|TCRG|TRD@|TRG@
- Anwendung:
- Flow Cytometry
- Klonalität:
- Monoclonal
- Konjugat:
- FITC
- Weitere Details:
- The G GammaD Delta T-cell receptor (TCR) is a heterodimer composed of G Gamma and D Delta chains, expressed on the T-cell surface and involved in antigen recognition. The engagement of the G GammaD Delta TCR with antigen triggers the phosphorylation of immunoreceptor tyrosine-based activation motifs (ITAMs) within the CD3 chains. Unlike A AlphaB Beta T cells, human G GammaD Delta T cells recognize and kill transformed cells in a manner unrestricted by human leukocyte antigen (HLA) presentation. G GammaD Delta T lymphocytes primarily develop in the thymus, where their defining receptor is generated through RAG-mediated recombination of a relatively limited repertoire of variable (V), diversity (D), and joining (J) gene segments. In addition to the T-cell receptor, G GammaD Delta T cells often express activating natural killer (NK) receptors, which bind to stress-induced surface molecules frequently expressed on malignant cells.
- Formulierung:
- Unmodified
- Host:
- Rabbit
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Non-human Primate
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Avoid freeze/thaw cycles.
- Hersteller:
- ABclonal Technology
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:A28422