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Antikörper

Myelin Basic Protein Mouse monoclonal antibody

Produktgrößen
5 ul
£ POA
A27589-5UL
20 ul
£152,00
A27589-20UL
100 ul
£336,00
A27589-100UL
500 ul
£1258,00
A27589-500UL
1000 ul
£2228,00
A27589-1000UL
Über dieses Produkt
SKU:
A27589
Zusätzliche Namen:
MBP
Anwendung:
ELISA, IHC-Paraffin, Immunofluorescence, Western Blot
Klonalität:
Monoclonal
Weitere Details:
The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes.
Formulierung:
Unmodified
Host:
Mouse
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Isotyp:
IgG
Molekulargewicht:
14-23 kDa
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Sequenz:
MGNHAGKRELNAEKASTNSETNRGESEKKRNLGELSRTTSEDNEVFGEADANQNNGTSSQDTAVTDSKRTADPKNAWQDAHPADPGSRPHLIRLFSRDAPGREDNTFKDRPSESDELQTIQEDSAATSESLDVMASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFGGDRGAPKRGSGKDSHHPARTAHYGSLPQKSHGRTQDENPVVHFFKNIVTPRTPPPSQGKGRGLSLSRFSWGAEGQRPGFGYGGRASDYKSAHKGFKGVDAQGTLSKIFKLGGRDSRSGSPMARR
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
ABclonal Technology
Typ:
Antibody: Monoclonal Antibody
  • Datenblatt des Herstellers:A27589
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