[KO Validated] MLKL Mouse monoclonal antibody
Produktgrößen
5 ul
£ POA
A27261-5UL
20 ul
£164,00
A27261-20UL
100 ul
£342,00
A27261-100UL
500 ul
£1532,00
A27261-500UL
1000 ul
£2704,00
A27261-1000UL
Über dieses Produkt
- SKU:
- A27261
- Zusätzliche Namen:
- hMLKL
- Anwendung:
- ELISA, IHC-Paraffin, Western Blot
- Klonalität:
- Monoclonal
- Weitere Details:
- This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene.
- Formulierung:
- Unmodified
- Host:
- Mouse
- Immunogen:
- Synthetic peptide. This information is considered to be commercially sensitive.
- Isotyp:
- IgG1
- Molekulargewicht:
- 54 kda
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- ABclonal Technology
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:A27261