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Antikörper

IL15 Rabbit polyclonal antibody

Produktgrößen
5 ul
£ POA
A24510-5UL
20 ul
£152,00
A24510-20UL
100 ul
£336,00
A24510-100UL
500 ul
£1258,00
A24510-500UL
1000 ul
£2228,00
A24510-1000UL
Über dieses Produkt
SKU:
A24510
Zusätzliche Namen:
IL-15|IL15|interleukin-15
Anwendung:
ELISA, Western Blot
Klonalität:
Polyclonal
Weitere Details:
The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported.
Formulierung:
Unmodified
Host:
Rabbit
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Isotyp:
IgG
Molekulargewicht:
18kDa
Aufreinigung:
Affinity Purified
Reaktivitäten:
Mouse
Sequenz:
NWVNVISDLKKIEDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISLESGDASIHDTVENLIILANNSLSSNGNVTESGCKECEELEEKNIKEFLQSFVHIVQMFINTS
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
ABclonal Technology
Typ:
Antibody: Polyclonal Antibody
  • Datenblatt des Herstellers:A24510
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