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Antikörper

TNF-A Alpha Rabbit monoclonal antibody

Produktgrößen
5 ul
£ POA
A21265-5UL
20 ul
£164,00
A21265-20UL
100 ul
£342,00
A21265-100UL
500 ul
£1532,00
A21265-500UL
1000 ul
£2704,00
A21265-1000UL
Über dieses Produkt
SKU:
A21265
Zusätzliche Namen:
DIF|TNF-alpha|TNF-A Alpha|TNFA|TNFSF2|TNLG1F
Anwendung:
ELISA, IHC-Paraffin
Klonalität:
Monoclonal
Weitere Details:
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, psoriasis, rheumatoid arthritis ankylosing spondylitis, tuberculosis, autosomal dominant polycystic kidney disease, and cancer. Mutations in this gene affect susceptibility to cerebral malaria, septic shock, and Alzheimer disease. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Formulierung:
Unmodified
Host:
Rabbit
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Isotyp:
IgG
Molekulargewicht:
26kDa
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Sequenz:
VRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
ABclonal Technology
Typ:
Antibody: Monoclonal Antibody
  • Datenblatt des Herstellers:A21265
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