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Antikörper

CBLB Rabbit polyclonal antibody

Produktgrößen
20 ul
£152,00
A2014-20UL
100 ul
£336,00
A2014-100UL
500 ul
£1258,00
A2014-500UL
1000 ul
£2228,00
A2014-1000UL
Über dieses Produkt
SKU:
A2014
Zusätzliche Namen:
Cbl-b|CBLB|Nbla00127|RNF56
Anwendung:
ELISA, Western Blot
Klonalität:
Polyclonal
Weitere Details:
This gene encodes an E3 ubiquitin-protein ligase which promotes proteosome-mediated protein degradation by transferring ubiquitin from an E2 ubiquitin-conjugating enzyme to a substrate. The encoded protein is involved in the regulation of immune response by limiting T-cell receptor, B-cell receptor, and high affinity immunoglobulin epsilon receptor activation. Studies in mouse suggest that this gene is involved in antifungal host defense and that its inhibition leads to increased fungal killing. Manipulation of this gene may be beneficial in implementing immunotherapies for a variety of conditions, including cancer, autoimmune diseases, allergies, and infections.
Formulierung:
Unmodified
Host:
Rabbit
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Isotyp:
IgG
Molekulargewicht:
125kDa/130kDa
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Sequenz:
NRTSQDYDQLPSCSDGSQAPARPPKPRPRRTAPEIHHRKPHGPEAALENVDAKIAKLMGEGYAFEEVKRALEIAQNNVEVARSILREFAFPPPVSPRLNL
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
ABclonal Technology
Typ:
Antibody: Polyclonal Antibody
  • Datenblatt des Herstellers:A2014