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Antikörper

TNFR2/TNFRSF1B Rabbit monoclonal antibody

Produktgrößen
5 ul
£ POA
A19127-5UL
20 ul
£164,00
A19127-20UL
100 ul
£342,00
A19127-100UL
500 ul
£1532,00
A19127-500UL
1000 ul
£2704,00
A19127-1000UL
Über dieses Produkt
SKU:
A19127
Zusätzliche Namen:
CD120b|p75|p75TNFR|TBPII|TNF-R-II|TNF-R75|TNFBR|TNFR1B|TNFR2|TNFR2/TNFRSF1B|TNFR80
Anwendung:
ELISA, Western Blot
Klonalität:
Monoclonal
Weitere Details:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
Formulierung:
Unmodified
Host:
Rabbit
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Isotyp:
IgG
Molekulargewicht:
68kDa
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Sequenz:
RASTGSSDSSPGGHGTQVNVTCIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQVPFSKEECAFRSQLETPETLLGSTEEKPLPLGVPDAGMKPS
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
ABclonal Technology
Typ:
Antibody: Monoclonal Antibody
  • Datenblatt des Herstellers:A19127
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