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Antikörper

PXR Rabbit polyclonal antibody

Produktgrößen
20 ul
£151,00
A17038-20UL
100 ul
£336,00
A17038-100UL
500 ul
£1258,00
A17038-500UL
1000 ul
£2228,00
A17038-1000UL
Über dieses Produkt
SKU:
A17038
Zusätzliche Namen:
BXR|ONR1|PAR|PAR1|PAR2|PARq|PRR|PXR|SAR|SXR
Anwendung:
ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Klonalität:
Polyclonal
Weitere Details:
This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized.
Host:
Rabbit
Immunogen:
This information is considered to be commercially sensitive.
Isotyp:
IgG
Molekulargewicht:
50kda
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
ABclonal Technology
Typ:
Antibody: Polyclonal Antibody
  • Datenblatt des Herstellers:A17038