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Antikörper

Cortactin Rabbit polyclonal antibody

Produktgrößen
20 ul
£152,00
A15054-20UL
100 ul
£336,00
A15054-100UL
500 ul
£1258,00
A15054-500UL
1000 ul
£2228,00
A15054-1000UL
Über dieses Produkt
SKU:
A15054
Zusätzliche Namen:
Cortactin|EMS1
Anwendung:
ELISA, IHC-Paraffin, Western Blot
Klonalität:
Polyclonal
Weitere Details:
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.
Formulierung:
Unmodified
Host:
Rabbit
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Isotyp:
IgG
Molekulargewicht:
85kDa
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Sequenz:
MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRENVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQRDYSKGFGGKYG
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Hersteller:
ABclonal Technology
Typ:
Antibody: Polyclonal Antibody
  • Datenblatt des Herstellers:A15054