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Antikörper

SERPINC1 Rabbit monoclonal antibody

Produktgrößen
5 ul
£ POA
A11249-5UL
20 ul
£164,00
A11249-20UL
100 ul
£342,00
A11249-100UL
500 ul
£1532,00
A11249-500UL
1000 ul
£2704,00
A11249-1000UL
Über dieses Produkt
SKU:
A11249
Zusätzliche Namen:
AT3|AT3D|ATIII|ATIII-R2|ATIII-T1|ATIII-T2|SERPINC1|THPH7
Anwendung:
ELISA, IHC-Paraffin, Western Blot
Klonalität:
Monoclonal
Weitere Details:
The protein encoded by this gene, antithrombin III, is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. Numerous mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency which constitutes a strong risk factor for thrombosis. A reduction in the serum level of this protein is associated with severe cases of Coronavirus Disease 19 (COVID-19).
Formulierung:
Unmodified
Host:
Rabbit
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Isotyp:
IgG
Molekulargewicht:
58kDa
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Sequenz:
MYSNVIGTVTSGKRKVYLLSLLLIGFWDCVTCHGSPVDICTAKPRDIPMNPMCIYRSPEKKATEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLAD
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
ABclonal Technology
Typ:
Antibody: Monoclonal Antibody
  • Datenblatt des Herstellers:A11249
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