Host pathway in proteome interaction screen |
Corresponding SARS-CoV-2 proteins interacting with host pathway |
DNA replication |
Nsp1 |
Epigenetic and gene expression regulators |
Nsp5, Nsp8, Nsp13 |
Vesicle trafficking |
Nsp6, Nsp7, Nsp10, Nsp13, Nsp15, Orf3a, Orf8 |
Lipid modification |
Spike |
RNA processing and regulation |
Nsp8 |
Ubiquitin ligases |
Orf10 |
Host signaling |
Nsp8, Nsp13, Orf9b |
Nuclear transport machinery |
Nsp9, Nsp15, Orf6 |
Cytoskeleton |
Nsp1, Nsp13 |
Mitochondria |
Nsp4, Nsp8, Orf9c |
Extracellular matrix |
Nsp9 |