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B7-H3

B7-H3

Our Immune Checkpoint Partners

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  • Bio X Cell
  • ACRO Biosystems
  • Arigo Bio
  • Cusabio

B7-H3, also referred to as CD276, is a member of the B7 family. While many molecules within this family are known to interact with immune checkpoints such as CD28, CTLA-4 and PD-1, the receptor for B7-H3 has not yet been fully characterised. B7-H3 is induced on antigen presenting cells by inflammatory cytokines and plays an important role in inhibiting T-cell function. It is also over-expressed within many human cancers, highlighting its importance as a therapeutic target to reduce cancer cell proliferation, progression, and metastasis.

B7-H3 related antibodies from preferred suppliers:

BE0124 - inVivoMAb anti-mouse CD276 (B7-H3) - The MJ18 (clone) monoclonal antibody reacts with mouse CD276 also known as B7-H3

ARG52539 - anti-CD276 / B7-H3 antibody [SP206] - The clone is SP206 and the immunogen is a synthetic peptide derived from human B7-H3 protein.

ARG23451 - anti-CD276 / B7-H3 antibody [MIH42] (PE)PE-conjugated mouse monoclonal antibody [MIH42] recognizes CD276 / B7-H3, clone MIH42 also detects CD276

Below are more purified versions:

for more information on the differences between InVivoMAb and InVivoPlus please click HERE!

- ARG23659 - anti-CD276 / B7-H3 antibody [MJ18] (low endotoxin)Azide free rat monoclonal antibody [MJ18] recognizes CD276 / B7-H3. This product specifically recognizes mouse CD276

B7-H3 related proteins from preferred suppliers:

- B73-M5255 - Mouse B7-H3 / CD276 Protein, Fc Tagis expressed from human 293 cells (HEK293). It contains AA Val 29 - Phe 244 (Accession # NP_598744). This protein carries a human IgG1 Fc tag at the C-terminus.

- B73-M52H4 - Mouse B7-H3 / CD276 Proteinis expressed from human 293 cells (HEK293). It contains AA Val 29 - Phe 244 (Accession # NP_598744). This protein carries a polyhistidine tag at the C-terminus.

- B7B-H5258 - Human B7-H3 (4Ig) / B7-H3b Protein, Fc Tagis expressed from human 293 cells (HEK293). It contains AA Gly 27 - Thr 461 (Accession # Q5ZPR3-1). This protein carries a human IgG1 Fc tag at the C-terminus.

B7-H3 related conjugated proteins:

- B73-H82E6 - Biotinylated Human B7-H3 / CD276 Protein, Avitag™,His Tagis expressed from human 293 cells (HEK293). It contains AA Leu 29 - Pro 245 (Accession # Q5ZPR3-2). This protein carries an Avi tag (Avitag™) at the C-terminus, followed by a polyhistidine tag.

- B7B-H82F5 - Biotinylated Human B7-H3 (4Ig) / B7-H3b Protein, Fc,Avitag™ is expressed from human 293 cells (HEK293). It contains AA Gly 27 - Thr 461 (Accession # Q5ZPR3-1). This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™).

B7-H3 related ELISA kits from preferred suppliers:

- CSB-E14285h - Human Soluble CD276,sCD276/sB7-H3 ELISA Kit

CSB-EL004912MO - Mouse CD276 antigen(CD276) ELISA kit

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